Tramadol is usually prescribed in cases of moderate to severe pain. Belonging to the class of opiate anaglesics, Tramadol is an opioid prescription that usually binds with the brain receptors to control the sensations of pain and reduce it significantly. The synthetic opioid analgesic usually manages the pain erupting after a surgery and also works well for conditions like arthritis. Tramadol comes up with the extended release version that helps people experience pain relief for longer periods of time, preventing the frequent intake of the drug.
Tramadol can cause a range of side effects like respiratory depression, drug dependence, lungs and liver disorder and have to be administered carefully for the elderlies. Also, it is not to be administered for children below the age of 12.
Tramadol in Pregnant Women
The assessment of Tramadol by the FDA states that there is no substantial evidence or data to analyze the safety of Tramadol during pregnancy. But this inconclusiveness leads to a debate that Tramadol and Pregnancy might not be the much sought after combination. It is advised that women stop or avoid the consumption of Tramadol when they are pregnant and they could consult their doctors for other alternatives of pain during pregnancy. Tramadol is indeed addictive to a developing fetus as it is for a pregnant mother. Most reports claim that the frequent use of this drug by pregnant women can develop drug dependence in the babies after discontinuation of usage. The withdrawal symptoms are said to be exhibited by the newborn babies up to one month or so.
Since the drug has been placed under the category of C by the FDA, the use of Tramadol by pregnant women is not restricted if there are chances for positive results. However, this treatment must be undertaken with the supervision of a doctor. Tramadol can also be passed on to the breast milk and hence, women must avoid Tramadol while breastfeeding. The indications of tramadol in the milk can be seen in the babies in the form of sleepiness, breathing difficulties and sedation. With these potential risks, the right answer for the question if tramadol can be consumed by pregnant women would be that the benefits have to outweigh the risks since it involves not only the life of the mother but also that of the unborn baby.
Side Effects of Tramadol
Some of the common side effects of Tramadol might include Stomach pain, aggressiveness, anxiety, constipation, diarrhea, dizziness, irritability, fever, headache, muscle pain, unusual drowsiness, Nausea, Skin itching and occasional skin rashes.
Tramadol must not be administered or you will have to consult a doctor before consuming it in case of these conditions like alcohol addiction, drug dependence, asthma, seizures, serotonin syndrome, obstructive lung disease, reduction in renal function, sleep apnea, sudden withdrawal from drugs, depression, intestine blockage, liver hardening and any infections in the nervous system of brain and the spinal cord.
Tramadol might cause possible risks with people who use depression drugs like monoamine oxidase inhibitor. Respiratory depression that is life threatening has been discovered in the kids who were administered with Tramadol. The elderly might face side effects with tramadol due to reduced renal function and metabolism. Also, elderly patients might suffer from gastrointestinal side effects like constipation.
Interaction of Tramadol with other drugs
Drug interactions with tramadol can be very deadly owing to the fact that the breakdown of the drug is very much unpredictable. For example, if you are an ultra-rapid metabolizer, you should refrain from the use of Tramadol since it can cause fatal respiratory overdose.
Tramadol is known to have drug interactions with the ones that affect the 3A4, 2D6 and the cytochrome P450 enzymes. Hundreds of drugs come under these categories and hence, it is important that you consult with the doctor or your pharmacist for drug interactions.
Drugs like ketoconazole and erythromycin can modify the blood levels of tramadol causing opioid toxicity or opioid withdrawal at extreme levels. Also, all types of anti-depressants must not be used with tramadol or tramadol must not be consumed within 14 days of taking an inhibitor for depression.
Tramadol must not be combined with any CNS depressant drugs and alcohol, while the drug must be avoided while driving, operating machines and indulging in other hazardous activities. A profound sense of clarification is necessary before you proceed to consume Tramadol in these cases only under the direct supervision of a doctor.