Canadian Tramadol No Rx
Differences in Oral vs Intravenous Tramadol
Tramadol is available in the market as the hydrochloride salt and is available in different brand names. It is very similar to codeine and morphine and it is a non-narcotic type drug. It is indicated for the treatment of mild to severe pain which can be acute or chronic.
Tramadol is available in many pharmaceutical forms such as tablets, capsules, intravenous, intramuscular, subcutaneous injections, rectal suppositories, sublingual drips and for intranasal administration. It is available as both immediate release formulation and controlled release formulation from online portals.
With the increase in technology, people are aware that one can Order Tramadol from home through online shopping by visiting one of the reputed online stores. Controlled release formulations are better tolerated than the immediate release dosage forms. It is usually indicated in combination with paracetamol.
Opioid-like effects: Oral Tramadol has low abuse potential
There are no changes in the pharmacokinetics of Tramadol in adults and children after oral and intravenous administration. The pharmacological effects of this drug differ when the drug is given after oral and parenteral administration.
Oral Tramadol has low abuse potential in comparison to opioid morphine. These opioid effects are produced after oral administration and this is not seen when the drug is administrated by a parenteral route such as intravenous injection.
Opioids effects are usually mild even if they appear after intravenous administration.
There are many orally administered dosage forms of Tramadol tablets, capsules, coated or uncoated chewable tablets, effervescent tablet, and powders, oral liquids with or without alcohol.
Intravenously administered Tramadol is 30% more potent
In a study published in Journal of Oral Maxillofacial Surgery Aug2005, which was conducted in patients for preventing pain after third molar surgery, the aim of which was to compare the power of single-dose preoperative intravenous Tramadol versus oral.
It was concluded that the oral was not as efficacious as that of intravenous Tramadol in preventing pain following third molar surgery. The bioavailability of the two dosage forms is different.
The authors concluded that preoperative intravenous Tramadol is more powerful than oral for preventing the after pain following third molar surgery. However, there is a difference in the availability of both the formulations of up to 30%.
Quicker pain relief from Tramadol when administered intravenously
Intravenous injection is administered to provide quick relief. The intravenously administered drug is 30% more potent than that of orally administered drug.
Tramadol dosage adjustment is much easier by IV route
When Tramadol is administered under schedule IV, the dosage can be changed adjustment according to the age (only adults should be given this drug), type of pain (chronic or acute), pain intensity and the sensitivity of the drug to the patient. Doctors normally prescribe to buy Tramadol 100mg for treating pain.
Tramadol is administered by slow IV injection and the drug lasts in the blood for about four to eight hours. No more than 400 mg of the drug to be administered.
An Oral dosage form of Tramadol should not be crushed such that tablets and the powder form should not be inhaled or dissolved in any solvent but to be administered properly. The inhaled or administered form can cause serious side-effect when compared to an oral dosage form.